The Biden administration asked the Supreme Court to overturn a lower court’s ruling that reversed regulations that made abortion pill mifepristone easier to obtain.

The case, to be heard on March 26, is the Supreme Court’s most important abortion-related case since its decision in June 2022 in Dobbs v. Jackson Women’s Health Organization, which overturned Roe v. Wade (1973) and found that there was no right to abortion in the U.S. Constitution. The ruling returned the regulation of abortion to the states.

A medication abortion generally involves the use of mifepristone, which blocks the hormone progesterone, and misoprostol, which induces contractions. Mifepristone is also known as mifeprex and RU-486. Misoprostol, which is widely available because it has many medical uses, isn’t an issue in the current litigation.

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